Danish Pharmacovigilance Update June 2014

News from the EU

• Potentially life-threatening accidental exposure to fentanyl patches (Durogesic® etc.)
• Combined use of medicines affecting the renin-angiotensin system (RAS) is restricted
• EU starts review of cardiovascular risks from long-term use with high doses of ibuprofen
• EU's list of recommendations on safety signals

News from the DHMA

• Dose errors involving fosphenytoin (Pro-Epanutin)
• Olanzapine prolonged-release injection (Zypadhera®) and post-injection syndrome
• Childhood vaccinations and adverse reactions in Q1 of 2014

News in brief

• Most recent Direct Healthcare Professional Communications (DHPCs)