Danish Pharmacovigilance Update, 18 October 2012

15 November 2012

In this issue of Danish Pharmacovigilance Update:

  • Risk of developing hepatotoxicity in patients undergoing treatment with agomelatine (Valdoxan®) (front page)
  • Cases of lactic acidosis in patients undergoing treatment with metformin for the treatment of type 2 diabetes (pp 2-3)
  • Use of MAOIs (monoamino oxidase inhibitors) and other antidepressants (p 4)
  • Restricted indications for trimetazidine (Vastarel®) (p 5)
  • Report of development of jaundice following initiation of treatment with medicines containing amoxicillin plus clavulanic acid (p 6)
  • Childhood vaccinations and adverse reactions in the second quarter of 2012 (pp 7-9)
  • Information on the safety of HPV vaccines (p 10)
  • Doctors in Denmark follow new recommendations for contraceptive pills (p 10)

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